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butabarbital will lower the level or influence of sulfamethoxazole by influencing hepatic enzyme CYP2C9/ten metabolism. Insignificant/Importance Unidentified.butabarbital will lower the level or effect of pioglitazone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.Butabarbital belongs to your group o